Fernando Llorente, who has been linked with several Premier League clubs including Arsenal and Manchester United, wants to leave Athletic Bilbao, the club have confirmed.
Bilbao president Josu Urrutia has confirmed that Llorente, who has just one year left on his current deal at San Mames, has no plans to sign a new contract and wants to leave.
Reports in Spain last week suggested Llorente had rejected Bilbao's latest contract offer.
As well as Arsenal and Man Utd, the likes of Manchester City and Juventus have also been linked with the Spain international.
And Urrutia, who last month stated Llorente would not be sold this summer unless his €36million buy-out clause was met, told reporters on Monday: "We spoke with him during last season and made him see how important it was that he renewed [his contract].
"He told us that after the European Championships he would let us know and ten days ago I received a call and his agents told me that there was no financial reason for him to continue [with Athletic].
"But what was even more important for him was to have the guarantee of challenging for championships and success.
"I let him know how disappointed I was but he told me the decision was final."
It has been claimed that Juventus have tabled a €16m bid for Llorente, but Urrutia is still insisting the €36m release clause is to be met.
"I am not speaking with any clubs because Athletic is not a selling club," he added.
"For him to leave Athletic, the player has not to want to be with us and the clubs that want him have to pay the release clause in his contract.
"Aside from that, for us it's a totally negative response and it's a blow to Athletic and a massive institutional failure because our reason for being is to compete in a different way.
"I still want Llorente to stay here. In interviews and recordings he has said that he wants to stay. Now he has told me that he wants to go. I think everyone will have done everything they could.
"It's not a case of throwing in the towel, it's that the player has told me the decision is final. During the last year the feeling was that questions could have led us to an economic agreement and now it seems that is not the case."