Santos star Ganso, who has been linked with Chelsea and Manchester United, has played his last game for the South American club.
However, whether the Brazil international will seek a move to the Premier League remains to be seen.
Both clubs have been monitoring the highly-rated 22-year-old for some time, as have the likes of Barcelona, Real Madrid, and Porto.
Santos had been keen for the Brazil international, who is under contract until 2015, to sign a longer-term deal to given them even greater security, but last week he snubbed the offer put to him, which according to reports was worth around £30,000 a week.
Santos president Luis Alvaro Ribeiro later revealed Ganso would be made available for transfer as a result of his contract snub.
And according to to Delcir Sonda, the owner of investment company DIS that own 55 per cent of Ganso's economic rights, the player will not feature for the Brazilian club again.
Sonda, who has claimed the player is disillusioned with Santos giving more attention to compatriot Neymar, told Radio Estadao ESPN: "He [Ganso] won't play for Santos again. That's definite.
"Ganso is annoyed with Santos. They came up with a project for Neymar, but forgot about him."
Despite the interest from across Europe, Sonda also suggested the player could remain in Brazil.
"Ganso could play for Internacional," he added.
"I'm negotiating with Santos. He wants to leave, but stay in Brazil for another year."
Tottenham have also shown interest in the playmaker.